LPM filter cartridges are characterized by high-performance, hydrophilic mixed cellulose esters membrane, offering high flow rates, low protein adsorption and superior microbiological safety. These filters are designed to reduce costs and are especially suited for in prefiltration of vaccines.

Features and Benefits
● Low protein binding
● Superior throughputs and cost-effective
● High retention efficiency for more critical degrees of prefiltration

Quality
● Cartridges produced in a controlled environment
● Manufactured according to ISO9001 certified Quality Management System

Ordering Information
LPSL Low Extractable and Longer Service Life Filter Cartridge for Plasma Fractionation

Application：
• Plasma Fractionation
• Sterile Injection Powder
• Vaccines
• Sterile Injection Powder
• Small & Large Volume Parenterals
• Plasma Fractionation
• Ophthalmic Solutions
• Facilities Water
• Cell Culture Media Preparation
• Active Pharmaceutical Ingredients
• Beer Filtration
• Wine Filtration
• Bottled Water Filtration
• Soft Drink Filtration
• Dairy Filtration
• High Fructose Syrup Filtration
• Semicon Filtration
• Ultrapure/DI Water Filtration
• Photoresist Filtration
• Display Filtration
• CMP Slurry Filtration
• Inkjet Inks Filtration
• Water Filtration
• Chemicals Filtration

LPSL Low Extractable and Longer Service Life Filter Cartridge for Plasma Fractionation

Materials of Construction
Membrane	Hydrophilic   MCE
Support	PP
Core,   Cage and Drainage	PP
End   Caps	PP   (222/226 with encapsulated stainless steel reinforcing ring)
O-rings/Gasket	Silicone/EPDM/Viton
Sealing   Technology	Thermal   Bonding, No Adhesives
Dimensions
Diameter	Φ68
Length	5 inch, 10 inch, 20 inch, 30 inch, 40 inch
Filtration Area, ft2
≥ 6.4 per 10-inch   element
Pore Size, μm
0.1, 0.22, 0.45, 0.65,   1.0, 3.0, 5.0
Maximum Differential Pressure
Forward:   4.2 bar @ 23 ℃; 1.5 bar @ 85 ℃
Bacterial Retention (for 0.1 and 0.22 μm only)
Passed the bacterial   challenge testing using Brevundimonas diminuta(ATCC19146) at a minimum challenge concentration of 1 x 105 CFU/cm2.
Extractables, per 10-inch cartridge
≤ 50 mg after 24-h soak in   water
Effluent Particle Level
Meets the requirements   of Chinese Pharmacopoeia 2010, Volume Ⅱ, appendix Ⅸ C.
Non-Fiber Releasing
Meets the criteria for   a “non-fiber releasing” filter as defined in 21 CFR 210.3 (b) (6).
Toxicity
Component materials   meet GB/T 14233.2of Chinese National Standard for Safety Tests.
TOC
< 500 ppb after a water flush of 60 liters per 10-inch cartridge
Multiple Sterilization Cycles
15 steam-in-place sterilization or autoclave cycles of 30 min at 123℃
Oxidizable Substances
Meets the criteria of Chinese Pharmacopoeia 2010, volume Ⅱ for purified water.
Bacterial Endotoxins
< 0.25 EU/ml as determined by the LAL test